Research paperDifferential distribution of free and bound glutathione and cyst(e)ine in human blood
References (60)
- et al.
The glutathione status of cells
Int Rev Cytol
(1978) - et al.
Glutathione disulfide variability in normal human blood
Anal Biochem
(1994) - et al.
The free amino acids of human blood plasma
J Biol Chem
(1954) - et al.
The reversible binding of half-cystine residues to serum protein, and its bearing on the cystine requirement of cultured mammalian cells
J Biol Chem
(1960) - et al.
Glutathione dependent control of protein disulfide-sulfhydryl content by subcellular fractions of hepatic tissue
Biochim Biophys Acta
(1977) - et al.
The formation of mixed disulfides in rat lung following paraquat administration
Biochim Biophys Acta
(1982) - et al.
Increase in hepatic mixed disulfides and glutathione levels elicited by paraquat
Biochem Pharmacol
(1982) - et al.
The occurrence of protein-bound mixed disulfides in rat tissues
Biochim Biophys Acta
(1973) - et al.
Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide
Biochem Pharmacol
(1983) - et al.
Effect of oxidant exposure on thiol status in the intestinal mucosa
Biochem Pharmacol
(1993)
Cellular mixed disulfides between thiols and proteins, and their possible implication for radiation protection
Biochem Pharmocol
(1968)
Reversible activation of soluble guanylate cyclase by oxidizing agents
Arch Biochem Biophys
(1992)
Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma
Anal Biochem
(1992)
Determination of reduced, oxidized and protein-bound glutathione in human plasma with precolumn derivatization with monobromobimane and liquid chromatography
Anal Biochem
(1990)
Determination of cysteine, glutathione and N-acetylcysteine in plasma by ion-pair reversed-phase liquid chromatography and post-column derivatization
J Chromatogr
(1988)
Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects
Atherosclerosis
(1989)
Interrelations between plasma free and protein-bound homocysteine in homocystinuria
Metabolism
(1988)
Altered plasma free and protein-bound sulfur amino acid levels in patients undergoing maintenance hemodialysis
Am J Clin Nutr
(1987)
A method for measurement of free and bound plasma cyst(e)ine
Anal Biochem
(1981)
Glutathione and γ-glutamylcysteine in whole blood, plasma and erythrocytes
Clin Chim Acta
(1978)
The distribution of free amino acids between erythrocytes and plasma in man
J Biol Chem
(1951)
Analysis of biological thiols: Derivatization with monobromobimane and separation by reverse-phase high-performance liquid chromatography
Anal Biochem
(1981)
The distribution of amino acids between plasma and erythrocytes
Clin Chim Acta
(1980)
The effects of changes in plasma amino acid concentrations on erythrocyte amino acid content
Clin Biochem
(1990)
Formation of disulfide bonds between glutathione and membrane SH groups in human erythrocytes
Biochim Biophys Acta
(1979)
The sulfur chemistry of proteins
Covalent binding of glutathione to hemoglobin
J Biol Chem
(1986)
Dynamic state of glutathione in blood plasma
J Biol Chem
(1980)
The level and half-life of glutathione in human plasma
FEBS Lett
(1980)
Manifestations of changes in the G-SH-G-S-S-G status of biological systems
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