Aspirin in coronary heart disease
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Long-term use of cardiovascular drugs challenges for research and for patient care
2015, Journal of the American College of CardiologyCitation Excerpt :Although the average follow-up in RCTs is limited, these medications are often administered open-endedly over many years. Table 2(11,12,17,23–49) shows an overview of some landmark RCTs that demonstrated the efficacy of aspirin, statins, beta-blockers, and ACE inhibitors in post-MI (and stable CHD) patients. A good example of this problem is a meta-analysis published in 2010 on the use of statins as primary and secondary prevention, in which the median follow-up across 26 trials was 4.9 years (2).
Antiplatelet Therapy
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