Journal of Molecular Biology
Volume 228, Issue 4, 20 December 1992, Pages 1163-1176
ArticleRole of B13 Glu in insulin assembly: The hexamer structure of recombinant mutant (B13 Glu → Gln) insulin☆
Dedicated to Dietrich Brandenburg on the occasion of the 60th anniversary of his birthday.
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This research has been supported by the Juvenile Diabetes Foundaton (New York), the Medical Research Council and the Science and Engineering Research Council of the U.K. and the Deutsche Forschungsgemeinschaft (Wo 152/8-6). The discussions with Professor Michael Dunn, Professor Dorothy Hodgkin, Professor Don Steiner and Professor Howard Tager have greatly helped in the progress of the research and preparation of the paper. Atomatic co-ordinates and structure factors have been deposited with the Protein Data Bank. Brookhaven National Laboratory (Bernstein et al., 1977), and are available in machine readable form from the Protein Data Bank, Brookhaven or one of the affiliated centres at Melbourne or Osaka.
Copyright © 1992 Published by Elsevier Ltd.