The influence of histocompatibility and transplant site on parathyroid allograft survival☆
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Cited by (29)
Parathyroid allotransplantation to treat post-thyroidectomy hypoparathyroidism: A review of case studies
2021, SurgeonCitation Excerpt :The cultured and cryopreserved parathyroid tissues were obtained from donor patients undergoing parathyroidectomy for secondary hyperparathyroidism. Parathyroids are immunologically privileged and it is important that the tissues are histocompatible as even weak histoincompatibility can affect the uptake of transplanted tissues.38,39 A single study proposed that the reason for inconsistencies in parathyroid allograft survival may be explained by the variation in lymphatic revascularization.38
Induction of tolerance to parental parathyroid grafts using allogeneic thymus tissue in patients with DiGeorge anomaly
2011, Journal of Allergy and Clinical ImmunologyCitation Excerpt :Animal models have yielded important insights regarding factors that contribute to rejection of, as opposed to tolerance toward, allogeneic parathyroid grafts. Not long after the MHC antigens were discovered, it was demonstrated that the degree of histocompatibility between the recipients and donors plays a significant role in determining long-term parathyroid graft survival.7 This understanding has resulted in efforts to reduce recipient allorecognition toward mismatched parathyroid graft MHC antigens.
Recent evidence for immune privilege in the testis
1990, Journal of Reproductive ImmunologyImmunologically privileged sites
1978, Advances in Immunology
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Supported in part by USPHS grant AI09275.