Autonomic neuropathy, I. Clinical features, investigation, pathophysiology, and treatment

doi:10.1016/0022-510X(95)00355-6

Journal of the Neurological Sciences

Volume 137, Issue 2, May 1996, Pages 79-88

https://doi.org/10.1016/0022-510X(95)00355-6 Get rights and content

Abstract

Autonomic dysfunction is a common complication of peripheral neuropathies. It is often of little clinical importance, but some conditions may cause profound disturbance of autonomic function, including postural hypotension, impotence and impairment of heart rate and bladder and bowel control. Autonomic function can be evaluated by a number of investigations, some of which can be performed in a neurophysiology laboratory. Diseases that primarily affect small nerve fibres or cause acute demyelination of small myelinated fibres are most likely to cause autonomic dysfunction. Management includes treating the underlying cause and symptomatic therapy.

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Review articleAutonomic neuropathy, I. Clinical features, investigation, pathophysiology, and treatment

Abstract

Gastroenterology

J. Urol.

J. Urol.

J. Urol.

Am. J. Med.

Am. J. Med.

J. Neurol. Sci.

J. Urol.

J. Urol.

J. Urol.

J. Urol.

J. Urol.

J. Urol.

J. Auton. Nerv. Syst.

Lancet

J. Urol.

J. Urol.

Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control

Science

Alpha-adrenergic agents in urinary disorders of the proximal urethra. Part II. Urethral obstruction due to ‘sympathetic dyssynergia’

Br. J. Urol.

Management of postural hypotension

Dopamine-beta-hydroxylase deficiency in humans

Neurology

The diagnosis and treatment of patients with neurologic dysfunction of the urinary bladder

Structural and chemical organisation of the autonomic nervous system with special reference to non-adrenergic, non-cholinergic transmission

Inability to constrict actively the superior mesenteric artery in human autonomic failure

J. Physiol. (Lond.)

Autonomic innervation of the eye

The pressor actions of noradrenaline angiotensin II in chronic autonomic failure treated with indomethacin

Br. J. Clin. Pharmacol.

Fate of patients started on clean intermittent self-catheterisation therapy 10 Years Ago

J. Urol.

Clinical presentations of diabetic autonomic failure

Development of urinary bladder dysfunction in diabetes mellitus

Ann. Intern. Med.

Cardiovascular responses to sustained handgrip in normal subjects and in patients with diabetes mellitus: a test of autonomic function

Clin. Sci. Mol. Med.

Immediate heart-rate response to standing: simple test for autonomic neuropathy in diabetics

Br. Med. J.

Management of orthostatic hypotension

Treatment of diabetic diarrhea with clonidine

Ann. Intern. Med.

The treatment of autonomic dysfunction

J. Clin. Neurophysiol.

Spectral analysis of heart rate in diabetic autonomic neuropathy

Arch. Neurol.

Treatment of diabetic cystopathy

Ann. Intern. Med.

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Circ. Res.

Pathological changes in the vagus nerve in diabetes and chronic alcoholism

J. Neurol. Neurosurg. Psychiatry

Topographic studies of disturbances of sweat secretion after complete lesions of peripheral nerves

J. Neurol. Neurosurg. Psychiatry

Diabetic gastroparesis from autonomic neuropathy: surgical considerations and changes in vagus nerve morphology

J. Neurol. Neurosurg. Psychiatry

Review article
Autonomic neuropathy, I. Clinical features, investigation, pathophysiology, and treatment