The effect of physical training on insulin production in obesity☆
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2015, Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular DiseaseChange of energy expenditure from physical activity is the most powerful determinant of improved insulin sensitivity in overweight patients with coronary artery disease participating in an intensive lifestyle modification program
2012, Metabolism: Clinical and ExperimentalCitation Excerpt :However, given that our multivariate analyses showed that change in PAEE was a more important predictor of change in m-value than were changes in general or abdominal obesity indices, a direct effect of exercise is therefore postulated. More than 30 years ago, Bjorntorp and colleagues [46] demonstrated lower insulin concentrations in response to an oral glucose tolerance test after an exercise program in 10 obese patients (of whom 8 were women), who had no clinical cardiovascular disease or other conditions that would prevent them from intensive physical training. Patients were instructed not to restrict their diet during the investigation.
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Supported by Grant B70-19X-251-07B from the Swedish Medical Research Council.
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Per Björntorp, M.D., Ph.D.: Assistant Professor of Experimental Medicine.
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Kristina de Jounge; Physiotherapist.
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Lars Sjöström, M.D.: Resident.
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Lars Sullivan, M.D.: Resident.