Elsevier

Metabolism

Volume 35, Issue 11, November 1986, Pages 981-983
Metabolism

Preliminary report
Muscle energy metabolism in uremia

https://doi.org/10.1016/0026-0495(86)90032-6Get rights and content

Abstract

Energy-rich phosphagens were measured in 11 patients with end-stage chronic renal failure and 11 nonuremic subjects. A significant decrease of ATP, phosphocreatine, total adenine nucleotides, lactate, and energy charge was found. The present results can be referred both to glycolytic sequence disturbances and to the lack of substrates characteristic of uremia.

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Supported by CNR Grant Relazioni Internazionali 8300364.04.

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