Research paper
DNA adducts from chemotherapeutic agents

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      Additionally, it may cause “DNA cross-linking from one guanine's N-7 position to another”, making it difficult to manufacture or transduce DNA from strand to strand. Finally, Alkeran is capable of inducing a broad variety of alterations in its action against cancer [49,50]. The establishment of hydrogen bonds inside a molecule has a significant impact on both the structure and characteristics of the molecule.

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    Haddow Laboratories, Institute of Cancer Research, Cotswold Road, Sutton, Surrey SM2 5NG, UK. Tel.: +44 181 643 8901. ext. 4660; Fax: +44 181 770 7290.

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