Elsevier

Survey of Ophthalmology

Volume 21, Issue 1, July–August 1976, Pages 18-44
Survey of Ophthalmology

Review
Visually evoked potentials: Theory, techniques and clinical applications

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Abstract

The visually evoked potential (VEP), the recording of which has recently been made possible by the development of computer averaging techniques, is a gross electrical signal generated by the occipital region of the cortex in response to visual stimulation. It is more specific than the electroencephalogram (EEG) and more sensitive to changes in the visual stimulus; thus, it can provide ophthalmologists and vision researchers with information about the human visual system that is unavailable by other methods. Clinically, the VEP is of special value in the areas of refraction, infant acuity, diseases of the optic nerve, color blindness, amblyopia and field defects. Theory, techniques and instrumentation are described, and applications of the VEP to clinical situations and to vision research are discussed.

References (135)

  • MR Harter et al.

    Effects of contour sharpness and check size on visually evoked cortical potentials

    Vision Res

    (1968)
  • MR Harter et al.

    Evoked cortical responses to checkerboard patterns: Effect of check size as a function of visual acuity

    Electroenceph Clin Neurophysiol

    (1970)
  • JAS Kinney et al.

    Visual evoked responses elicited by rapid stimulation

    Electroencephal Clin Neurophysiol

    (1973)
  • M Korth et al.

    Stimulus alternation and the Purkinje shift

    Vision Res

    (1976)
  • C Lombroso et al.

    Selective suppression of cerebral-evoked potentials to patterned light in amblyopia ex anopsia

    Electroenceph Clin Neurophysiol

    (1969)
  • JG May et al.

    Spectral sensitivity of the human VER obtained with an alternating barred pattern

    Vision Res

    (1970)
  • JG May et al.

    The visual evoked response obtained with an alternating barred pattern: Rate, spatial frequency and wavelength

    Electroenceph Clin Neurophysiol

    (1971)
  • WF Michael et al.

    Differences between the occipital distribution of upper and lower field pattern — evoked responses in man

    Brain Res

    (1971)
  • J Miller et al.

    Photic driving in amblyopia ex anopsia

    Am J Ophthalmol

    (1961)
  • P Padmos et al.

    Visually evoked cortical potentials to patterned stimuli in monkey and man

    Electroenceph Clin Neurophysiol

    (1973)
  • D Regan et al.

    Brightness contrast and evoked potentials

    J Opt Soc Am

    (1973)
  • E Adachi-Usami et al.

    VER threshold in different stages of optic neuritis

    Ophthalmol Res

    (1972–1973)
  • GB Arden

    The visual evoked response in ophthalmology

  • GB Arden et al.

    Visually evoked responses in amblyopia

    Br J Ophthalmol

    (1974)
  • Arden GB, Faulkner DJ, Mair C: A versatile television pattern generator for visual evoked potentials. Br J Ophthalmol...
  • JC Armington

    Spectral sensitivity of simultaneous electroretinograms and occipital responses

    Vision Res Suppl 1, Clinical Electroretinography

    (1966)
  • JC Armington et al.

    Simultaneously recorded retinal and cortical responses to patterned stimuli

    J Opt Soc Am

    (1971)
  • P Asselman et al.

    Visual evoked responses in the diagnoses and management of patients with multiple sclerosis

    Brain

    (1975)
  • J Behrman et al.

    A clinical method for obtaining pattern visual evoked responses

  • Y Bornstein

    The pattern evoked responses (VER) in optic neuritis

    Albrecht v Graefes Arch Klin exp Ophthalmol

    (1975)
  • CM Bourassa et al.

    Photic-evoked cortical potentials in functional amblyopia

    Can J Ophthalmol

    (1971)
  • GS Brindley
  • H Burian et al.

    Cerebral electric response to intermittent photic stimulation in amblyopia ex anopsia: A preliminary report

    Arch Ophthalmol

    (1952)
  • F Campbell et al.

    Electrophysiological evidence for the existence of orientation and size detectors in the uman visual system

    J Physiol Lond

    (1970)
  • JM Cappin et al.

    Visual evoked responses in the assessment of field defects in glaucoma

    Arch Ophthalmol

    (1975)
  • CR Cavonius

    Evoked response of the human visual cortex: Spectral sensitivity

    Psychon Sci

    (1965)
  • WA Cobb et al.

    Cerebral potentials evoked by pattern reversal and their suppression in visual rivalry

    Nature

    (1967)
  • RM Copenhaver et al.

    Objective field testing: Occipital potential evoked from small visual stimuli

    J Am Med Assoc

    (1963)
  • RM Copenhaver et al.

    Factors affecting visually evoked cortical potentials such as impaired vision of varying etiology

    Invest Ophthalmol

    (1964)
  • RM Copenhaver et al.

    Electroperimetry: A laboratory method for the study of the visual field

  • A Cowey

    Projection of the retina onto striate and prestriate cortex in the squirrel monkey Saimiri Sciureus

    J Neurophysiol

    (1964)
  • OD Creutzfeld et al.

    Electrophysiology and topographical distribution of visual evoked potentials in animals

  • WW Dawson et al.

    Variation in human cortical response to patterns and image quality

    Invest Ophthalmol

    (1972)
  • S Duke-Elder

    The anatomy of the visual system

  • FH Duffy et al.

    Ametropia measurements from the visual evoked response

    Am J Optom Arch Am Acad Optom

    (1971)
  • RJ Ellingson

    Cortical electrical responses to visual stimulation in the human infant

    Electroenceph Clin Neurophysiol

    (1960)
  • RJ Ellingson

    Development of visual evoked responses in human infants recorded by a response averager

    Electroenceph Clin Neurophysiol

    (1966)
  • O Estevez et al.

    Relationship between pattern appearance-disappearance and pattern reversal responses

    Exp Brain Res

    (1974)
  • Cited by (0)

    Supported in part by NIH Research Grant EY-00926 and Career Development Award EY-70275.

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