Age-related changes in arterial wall mechanics and composition of NIA Fischer rats
References (33)
Effects of spontaneous hypertension and age on arterial connective tissue in the rat
Exp. Gerontol.
(1976)The aortic tunica media in aging rats
Exp. Mol. Pathol.
(1970)- et al.
The aortic tunica intima in young and aging rats
Exp. Mol. Pathol.
(1972) - et al.
Adrenergic-receptor activity and cyclic AMP metabolism in vascular smooth muscle; variations with age
Mech. Ageing Dev.
(1975) - et al.
The determination of collagen and elastin in tissues
J. Biol. Chem.
(1950) Changes in the elasticity of the aorta with age
Arch. Pathol.
(1940)- et al.
The effect of age on the elasticity of human iliac arteries
Can. J. Biochem. Physiol.
(1959) - et al.
Alterations with age in the viscoelastic properties of human arterial walls
Circ. Res.
(1966) Dependence of wall stress in the human thoracic aorta on age and pressure
Circ. Res.
(1967)- et al.
Age related changes in the mechanics of the aorta and pulmonary artery of man
J. Appl. Physiol.
(1974)
Static mechanical properties of the developing and mature rat aorta
Cardiovasc. Res.
Effects of age on the mechanical properties of rat carotid artery
Am. J. Physiol.
The aortic tunica media of the developing rat
Lab. Invest.
Effects of hypertension on the static mechanical properties and chemical composition of the rat aorta
Cardiovasc. Res.
Electron microscopy of the aorta in young and adult Chinese hamsters
Artery
Vascular contraction: Effect of age and extracellular calcium
Blood Vessels
Cited by (36)
Pyridoxamine prevents age-related aortic stiffening and vascular resistance in association with reduced collagen glycation
2011, Experimental GerontologyCitation Excerpt :Contradictory observations were reported in Fisher 344 rats: one study showed no change (Delp et al., 1998), another a slight decrease (Buñag et al., 1990), and yet another an increase (Yu et al., 1985) in the blood pressure with age. Other studies have also shown that aged Fisher 344 rats do not readily develop atherosclerosis (Coleman et al., 1977) and hypertension (Hall et al., 1976; Cox, 1983). In this current study, the aortic pressure profile did not change significantly as the rats aged.
Sustained sensorimotor impairments after endothelin-1 induced focal cerebral ischemia (stroke) in aged rats
2010, Experimental NeurologyThe elastic fibres: A regulator of normal and pathological ageing of elastic blood vessels
2009, Medecine et LongeviteGrowth hormone influences the content and composition of collagen in the aorta from old rats
2002, Mechanisms of Ageing and DevelopmentTwo new elastin cross-links having pyridine skeleton. Implication of ammonia in elastin cross-linking in vivo
2001, Journal of Biological ChemistryCitation Excerpt :In general, the elastin concentration decreases, and the collagen concentration increases until a certain age and then reaches a plateau (41-45). However, few studies have investigated the biochemical properties and the contents of elastin and collagen in the same vessel, and the results have been conflicting (41, 42, 45). The changes in the biochemical properties of collagen are characterized by the formation of cross-links, especially those derived from nonenzymatic glycation (19, 20).
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Maining address: Robert H. Cox, Ph.D., Bockus Research Institute, Graduate Hospital, 19th & Lombard Streets, Philadelphia, PA 19146, U.S.A.