Cell
ReviewA thousand and one protein kinases
References (71)
- et al.
Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor
J. Biol. Chem.
(1985) - et al.
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated protein kinase activity
J. Biol. Chem.
(1984) - et al.
A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles
J. Biol. Chem.
(1982) - et al.
Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and scu1+
Cell
(1987) - et al.
Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6
J. Biol. Chem.
(1986) - et al.
Drosophila melanogaster DNA clones homologous to the vertebrate oncogenes: evidence for a common ancestor to the src and abl cellular genes
Cell
(1983) - et al.
Enzymatically inactive pp60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region
Cell
(1987) - et al.
Cloning and expression of multiple protein kinase C cDNAs
Cell
(1986) - et al.
Factors affecting the activity of muscle phosphorylase b kinase
J. Biol. Chem.
(1959) - et al.
The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains
Cell
(1985)
Isolation and nucleotide sequence of a Saccharomyces cerevisiae protein kinase gene suppressing the cell cycle start mutation cdc25
J. Biol. Chem.
Dual regulation of the yeast CDC28-p40 protein kinase complex: cell cycle, pheromone, and nutrient limitation effects
Cell
Regulation of brain type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: a Ca2+-triggered molecular switch
Cell
Cloning of a Drosophila cDNA encoding a polypeptide similar to the human insulin receptor
Biochem. Biophys. Res. Commun.
Cloning of rat brain protein kinase C complementary DNA
FEBS Lett.
Two types of complementary DNAs of rat brain protein kinase C
FEBS Lett.
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
Cell
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis
Cell
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene
Cell
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation
Cell
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
Cell
Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase
Cell
An adenosine 3′,5′-monophosphate-dependent protein kinase from rabbit skeletal muscle
J. Biol. Chem.
Viral src gene products are related to the catalytic chain of mammalian cAMP-dependent protein kinase
Alternative 5′ exons in c-abi mRAN
Cell
β-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
Trends in oncogenes
Trends Genet
The molecular genetics of cancer
Science
Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity
Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase
Mol. Cell. Biol.
A yeast gene that is essential for release from glucose repression encodes a protein kinase
Science
The role of protein phosphorylation in the hormonal control of enzyme activity
Eur. J. Biochem.
Tyr527 is phosphorylated in pp60c-src: implications for regulation
Science
Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src
Mol. Cell. Biol.
Multiple, distinct forms of bovine and human-protein kinase C suggest diversity in cellular signaling pathways
Science
Cited by (878)
The active kinome: The modern view of how active protein kinase networks fit in biological research
2022, Current Opinion in PharmacologyCitation Excerpt :Historically, the study of protein kinases was directed first towards their involvement in protein kinase cascades as the mechanism of transducing and amplifying extracellular stimuli via activation of receptors coupled to protein kinases [19,20]. Protein kinase cascades, intrinsically necessary for signal amplification because of protein kinase bioenergetic constraints, were viewed later as distinct from protein kinase networks, the interactions serving as the primary mechanism by which a cell regulates physiologic processes [20,21]. In this fashion, protein kinase networks were first conceptualized in 1987, in a groundbreaking paper comparing protein kinase networks to transistor circuitry, the “signal” being protein phosphorylation and the “gain” being regulation of protein kinase activity within the network [21].
Live cell imaging of signaling and metabolic activities
2019, Pharmacology and TherapeuticsIdentification of novel physiological substrates of mycobacterium bovis BCG protein Kinase G (PknG) by label-free quantitative phosphoproteomics
2018, Molecular and Cellular ProteomicsHow many kinases are druggable? A review of our current understanding
2023, Biochemical JournalElectrical stimulation waveform-dependent osteogenesis on PVDF/BaTiO<inf>3</inf> composite using a customized and programmable cell stimulator
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