Elsevier

Psychiatry Research

Volume 32, Issue 1, April 1990, Pages 45-53
Psychiatry Research

Motor activity and tonic heart rate in panic disorder

https://doi.org/10.1016/0165-1781(90)90134-QGet rights and content

Abstract

Motor activity and tonic heart rate were monitored in 62 drug-free panic disorder patients and 40 normal control subjects. Mean daily activity, mean waking heart rate controlled for activity, and mean sleeping heart rate were determined. Panic disorder patients without phobic avoidance showed higher activity than control subjects or patients with limited or extensive avoidance. Similarly, an “inverted U” relationship between trait anxiety and activity was observed. On the other hand, neither mean waking nor sleeping heart rate showed significant differences between patients and controls, suggesting that the differences previously reported in laboratory studies result from anticipatory anxiety.

References (26)

  • Clark, D.B.; Taylor, C.B.; and Hayward, C. Naturalistic assessment of panic episodes: In: Ballenger, J., ed. The...
  • L.R. Derogatis

    SCL-90: Administration, Scoring and Procedures Manual-I for the Revised Version

    (1977)
  • E.L. Echandia et al.

    Behavioral responses of high and low active male rats to the chronic ingestion of despramine

    Pharmacology, Biochemistry and Behavior

    (1985)
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    Duncan B. Clark, Ph.D., is Assistant Professor of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA. C. Barr Taylor, M.D., is Associate Professor of Psychiatry; Chris Hayward, M.D., M.P.H., is Director, Comprehensive Medical Unit; Roy King, M.D., Ph.D., is Assistant Professor of Psychiatry; Walton T. Roth, M.D., is Professor of Psychiatry; and W. Stewart Agras, M.D., is Professor of Psychiatry, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA. Jürgen Margraf, Ph.D., is Assistant Professor of Psychology, and Anke Ehlers, Ph.D., is Assistant Professor of Psychology, Fachbereich Psychologie, Marberg, West Germany.

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