Review
NMDA receptors - their role in long-term potentiation

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Abstract

Long-term potentiation (LTP) has for a long time captured the imagination of neuroscientists as a model with which to probe the cellular mechanisms of learning and memory in the mammalian brain. In this article we describe the recent evidence that has revealed the pivotal role of NMDA receptors in the induction of LTP, and discuss the possible mechanisms involved in the maintenance of the potentiated state.

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