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Cardiovascular adaptations to obesity and arterial hypertension: detrimental or beneficial?

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Cited by (7)

  • Obesity Paradox in Patients with Hypertension and Coronary Artery Disease

    2007, American Journal of Medicine
    Citation Excerpt :

    Third, obese patients display a readily identifiable phenotype that is believed to reflect a high risk for cardiovascular disease, and they may receive or seek treatment earlier in the time course of disease, thereby altering the natural history of their disease when compared with lean patients (lead time bias). Fourth, it has been well documented that the hemodynamics of obesity hypertension are characterized by a high cardiac output, an expanded blood volume, and a lower systemic vascular resistance when compared with normal-weight patients.27-31 Because systemic resistance reflects the severity of hypertensive cardiovascular disease, the comparatively low values in obesity may translate into a better outcome in this population.

  • Weight science: Evaluating the evidence for a paradigm shift

    2013, Clinical Nutrition: The Interface Between Metabolism, Diet, and Disease
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