Trends in Biotechnology
UndercurrentsDetection of bacteria by transduction of ice nucleation genes
Reference (16)
- et al.
Trends Biochem. Sci.
(1989) - et al.
Gene
(1989) - et al.
FEMS Microbiol. Lett.
(1989) - et al.
Food Rev. Int.
(1988) - et al.
J. Bacteriol.
(1985) - et al.
Nature
(1985)
Cited by (52)
Replacement of antibodies with bacteriophages in lateral flow assay of Salmonella Enteritidis
2021, Biosensors and BioelectronicsBacteriophage-based advanced bacterial detection: Concept, mechanisms, and applications
2021, Biosensors and BioelectronicsCitation Excerpt :P22 infection in Salmonella led to ice crystal formation on the outer cell membrane. A detection limit of 10 cells/mL was reported in artificially contaminated eggs and raw meat samples (Wolber and Green 1990). A commercial assay based on ice nuclease P22 reporter phages was developed, and demonstrated potency to detect Salmonella with a limit of detection of less than 3 CFU/mL in 3 h (van der Merwe et al., 2014).
Recent advances in bacteriophage-based methods for bacteria detection
2018, Drug Discovery TodaySynthetic biology strategies towards the development of new bioinspired technologies for medical applications
2017, Bioinspired Materials for Medical ApplicationsPhage technology in high throughput screening for pathogen detection in food
2015, High Throughput Screening for Food Safety Assessment: Biosensor Technologies, Hyperspectral Imaging and Practical ApplicationsBacteriophage-based synthetic biology for the study of infectious diseases
2014, Current Opinion in MicrobiologyCitation Excerpt :A common design strategy is the creation of reporter-based constructs packaged within phage or phage-like particles that infect target cells and ultimately result in the production of fluorescent, colorimetric, or luminescent signals. Furthermore, sensor designs can include genetically engineered phage that express a product causing ice nucleation [110] or that incorporate tags for linking to detectable elements such as quantum dots [111]. Though most of these examples of specifically modified phages have been enabled by advancements in engineering and synthetic biology to achieve real-world applicability, the concept of using natural phage as sensing tools is not a new one.