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Cited by (11)
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP<sup>+</sup>/MPTP-induced neuronal death in multiple experimental models
2015, Free Radical Biology and MedicineCitation Excerpt :Mitochondrial complex I deficiency is one of the major clinical changes in PD patients, pointing toward a critical role of MPP+/MPTP in elucidating the possible pathogenesis mechanisms of neurodegenerative diseases [10,11]. In addition, the neurotoxicity and mechanisms of MPP+/MPTP have been well defined in various models [12–14]. Therefore, MPP+/MPTP-induced neurotoxicity in vitro and in vivo has been commonly used to evaluate neuroprotective candidates [15–17].
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