Elsevier

Neurobiology of Aging

Volume 12, Issue 6, November–December 1991, Pages 663-668
Neurobiology of Aging

Necessity of a more standardized microbiological characterization of rodents for aging studies

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Abstract

The establishement of germ-free, gnotobiotic, and SPF animal colonies is a major component of any effort to develop suitable animal models for aging research. Epidemic and endemic disease in laboratory animals can lead to unacceptable losses, contamination of research results, and exposure of staff and investigators to unnecessary health risks. Monitoring the health status and microbiological burden of the animals is particularly important. These issues are discussed, with accompanying guidelines and protocols in pragmatic, tabular form.

References (4)

  • M.A. Horan et al.

    Systems under stress: Infectious agents and host defenses

  • C. Rowlatt

    Problems associated with the development of a cology of aged mice for experimental purposes

    Age Ageing

    (1969)
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