Elsevier

Vaccine

Volume 14, Issue 3, February 1996, Pages 185-186
Vaccine

Short paper
Immunization coverage required to prevent outbreaks of dog rabies

https://doi.org/10.1016/0264-410X(95)00197-9Get rights and content

Abstract

WHO recommends that 70% of dogs in a population should be immunized to eliminate or prevent outbreaks of rabies. This critical percentage (pc) has been established empirically from observations on the relationship between vaccination coverage and rabies incidence in dog populations around the world. Here, by contrast, we estimate pc by using epidemic theory, together with data available from four outbreaks in urban and rural areas of the USA, Mexico, Malaysia and Indonesia. From the rate of increase of cases at the beginning of these epidemics, we obtain estimates of the basic case reproduction number of infection, R0, in the range 1.62–2.33, implying that pc lies between 39% and 57%. The errors attached to these estimates of pc suggest that the recommended coverage of 70% would prevent a major outbreak of rabies on no fewer than 96.5% of occasions.

References (11)

  • D. Waltner-Toews et al.

    An epidemic of canine rabies in Central Java, Indonesia

    Preventive Vet. Med.

    (1990)
  • M. Fekadu

    Canine rabies

  • World Health Organization

    Guidelines for Dog Rabies Control

    (1987)
  • G.W. Beran

    Urban rabies

  • R.F. Korns et al.

    Dog, fox and cattle rabies in New York State

    Am. J. Publ. Hlth

    (1948)
There are more references available in the full text version of this article.

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