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Magnesium: metabolism and hormonal regulation in different species

https://doi.org/10.1016/0300-9629(85)90478-5Get rights and content

Abstract

  • 1.

    1. The magnesium ion is of great importance in physiology by its intervention in 300 enzymatic systems, its membrane role and its function in neuromuscular excitability.

  • 2.

    2. The skeleton is the first pool of magnesium in the animal body.

  • 3.

    3. For intestinal absorption, renal metabolism, bone accretion and résorption, magnesium shows analogies with calcium.

  • 4.

    4. Magnesium exchange between extracellular, cellular and skeletal compartments are very precisely controlled.

  • 5.

    5. Parathyroid hormone, 1α,25-dihydroxy-vitamin D3. calcitonin and estrogens are the principal hormone systems implicated in magnesium metabolism.

  • 6.

    6. The kidney is the principal site of magnesium excretion and shows important magnesium regulation mechanisms.

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