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2022, Brain Research BulletinCitation Excerpt :Circumventricular organs (CVOs), median preoptic nucleus, and tissue surrounding the anteroventral third ventricle in the lamina terminalis (AV3V region) are brain regions in which the blood-brain-barrier is more permeable (Gross et al., 1987).
Inhibition of serum and glucocorticoid regulated kinases by GSK650394 reduced infarct size in early cerebral ischemia-reperfusion with decreased BBB disruption
2021, Neuroscience LettersCitation Excerpt :All samples were automatically corrected for quenching. The blood-brain transfer coefficient for 14C-AIB was determined assuming a unidirectional transfer of 14C-AIB over a ten-min period of the experiment using the equation described previously [10,11,27]: For tetrazolium staining, 2,3,5-triphenyltetrazolium chloride (Sigma) 0.05% solution in PBS was prepared and warmed to 37 °C [28].
Lysophosphatidic acid increased infarct size in the early stage of cerebral ischemia-reperfusion with increased BBB permeability
2020, Journal of Stroke and Cerebrovascular DiseasesRapamycin decreased blood-brain barrier permeability in control but not in diabetic rats in early cerebral ischemia
2017, Neuroscience LettersCitation Excerpt :This suggests a less important role of mTOR in altering BBB permeability in diabetes. Experimental conditions such as anesthetics, duration of anesthesia, blood pressure, blood gases, age, temperature, or species may alter BBB permeability [10,11]. The effects of experimental conditions on our data should be negligible because all experiments were performed under identical conditions.