Elsevier

Gene

Volume 46, Issues 2–3, 1986, Pages 297-300
Gene

Sequence of glutamine synthetase from Salmonella typhimurium and implications for the protein structure

https://doi.org/10.1016/0378-1119(86)90415-4Get rights and content

Abstract

To aid in the interpretation of the 3.5 Å resolution electron density map of glutamine synthetase (GS) from Salmonella typhimurium, the nucleotide sequence of the gene coding for this enzyme has been determined. The predicted sequence of 468 amino acids (Mr = 51628) has been compared to the sequence and sequence fragments reported by others for GS of Anabaena and Escherichia coli. The homology between the pairs of sequences is sufficiently strong to suggest that the overall three-dimensional structures of the three GS are similar. The predicted positions of α helices are in moderately good agreement with the electron-density map.

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