Acute mannitol intoxication in a patient with normal renal function

doi:10.1016/0735-6757(90)90091-D

The American Journal of Emergency Medicine

Volume 8, Issue 4, July 1990, Pages 338-339

https://doi.org/10.1016/0735-6757(90)90091-D Get rights and content

Abstract

A young, previously healthy patient with multiple trauma mistakenly received 400 grams of mannitol over a 3-hour period. The laboratory report of hyponatremia prompted treatment with hypertonic saline before the hyperosmolar state was recognized. The osmolal gap was 118. Mannitol toxication in a patient without preexisting renal failure is unusual. Identification of an abnormal osmolal gap and recognition of the hyperosmolar state is discussed.

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Brief reportAcute mannitol intoxication in a patient with normal renal function

Abstract

J Pediatrics

J Urol

Am J Med

J Urol

Am J Emerg Med

Mannitol intoxication in patients with renal failure

Arch Intern Med

Acute renal failure associated with mannitol intoxication

Arch Intern Med

Partition of the body fluids: Osmotic equilibria between extracellular and intracellular fluids

Brief report
Acute mannitol intoxication in a patient with normal renal function