Original articleImpact of referral bias on clinical and epidemiological studies of Alzheimer's disease☆
References (23)
Bias in analytic research
J Chron Dis
(1979)- et al.
Influence of referral bias on the apparent clinical spectrum of infective endocarditis
Am J Med
(1990) - et al.
Effects of referral bias on surgical outcomes: A population-based study of surgical patients 90 years of age or older
- et al.
Abdominal aortic aneurysms: The changing natural history
J Vase Surg
(1984) Limitations of the application of fourfold table analysis to hospital data
Biometrics
(1946)Selection bias in the referral of patients and the natural history of surgical conditions
- et al.
The patient record in epidemiology
Sci Am
(1981) - et al.
Lack of association between Alzheimer's disease and education, occupation, marital status, or living arrangement
Neurology
(1992) - et al.
Epidemiologic studies of dementia in Rochester, Minnesota
- et al.
Clinical risk factors for Alzheimer's disease: A population-based case-control study
Neurology
(1991)
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
Neurology
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2017, Alzheimer's and DementiaPhenotypes and body mass in women with polycystic ovary syndrome identified in referral versus unselected populations: systematic review and meta-analysis
2016, Fertility and SterilityCitation Excerpt :Berkson's bias, a form of selection bias, was first described in 1946 and questioned the validity of epidemiological studies performed in medical settings (60). Extensive evidence demonstrates that patients with Alzheimer's disease, cancer, and surgical conditions identified in clinical facilities are not necessarily representative of the same diagnoses in the general population (61–63). Cases identified in clinical settings tend to have a more severe manifestation of the disease and differ from the general population in socioeconomic variables.
Dementia severity and the longitudinal costs of informal care in the Cache County population
2015, Alzheimer's and DementiaCitation Excerpt :However, The Predictors Study drew dementia patients from academic clinical centers, whereas the French study drew dementia patients from a randomized clinical trial. Neither study's population is representative of typical community-dwelling dementia patients and their caregivers, for example, there is greater likelihood of individuals from clinic samples to be married and of higher socioeconomic status than persons drawn from the general community [11]. Recently Hurd et al. [5] estimated that the yearly cost of care attributable to dementia ranged from $41,689 to $56,689 (in 2010 dollars) depending on the method used to estimate informal caregiving costs.
Development of population research at Mayo Clinic
2014, Mayo Clinic Proceedings
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This study was supported in part by research grants NS17750, AG06786, and AG08031 from the National Institutes of Health, Bethesda, Maryland.