Biological predictors of 1-year outcome in schizophrenia in males and females
References (55)
- et al.
The timing of brain morphological changes in schizophrenia and their relationship to clinical outcome
Biol. Psychiatry
(1992) - et al.
Ventricular enlargement, neuropsychological status, and premorbid function in schizophrenia
Biol. Psychiatry
(1994) - et al.
Comparison of early and delayed inpatient dexamethasone suppression tests
Psychiatry Res.
(1989) - et al.
DST and schizophrenic symptomatology
Biol. Psychiatry
(1989) - et al.
Electroencephalographic sleep in schizophrenia: A critical review
Comp. Psychiatry
(1990) - et al.
Lateral ventricular enlargement associated with persistent unemployment and negative symptoms in both schizophrenia and bipolar disorder
Psychiatry Res.
(1984) - et al.
Effects of RS-86 on REM latency in schizophrenia
Psychiatry Res.
(1991) - et al.
Association between abnormal REM sleep and negative symptoms in schizophrenia
Psychiatry Res.
(1989) - et al.
Dexamethasone Suppression Test in Schizophrenia: Relationship to symptomatology, ventricular enlargement, and outcome
Biol. Psychiatry
(1991) - et al.
Muscarinic cholinergic hyperactivity in schizophrenia: relationship to positive and negative symptoms
Schizophr. Res.
(1991)
Cholinergic hyperactivity and negative symptoms: Behavioral effects of physostigmine in normal controls
Schizophr. Res.
Sleep onset REM periods in schizophrenic patients
Biol. Psychiatry
The Scale for the Assessment of Negative Symptoms
Gender and the course of schizophrenia: Differences in treated outcomes
Schizophr. Bull.
Course of illness and predictors of outcome in chronic schizophrenia: Implications for pathophysiology
Br. J. Psychiatry
A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility
Arch. Gen. Psychiatry
Abnormal DST results in patients with chronic schizophrenia
Am. J. Psychiatry
Gender, premorbid social functioning, and long-term outcome in DSM-III schizophrenia
Schizophr. Bull.
Dexamethasone suppression test in depression and other psychiatric illnesses
Br. J. Psychiatry
HPA axis reactivity and recovery from functional psychosis
Am. J. Psychiatry
A diagnostic interview: The schedule for affective disorders and schizophrenia
Arch. Gen. Psychiatry
Sleep patterns in schizophrenia: A selective review
Electroencephalographic sleep in young, never-medicated schizophrenics
Arch. Gen. Psychiatry
Empirical correction of seven myths about schizophrenia with implications for treatment
Acta Psychiatr. Scand. (Suppl.)
Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine
Arch. Gen. Psychiatry
Outcome predictors in acute schizophrenia: Prospective significance of background and clinical dimensions
J. Nerv. Ment. Dis.
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2020, Psychiatry ResearchCitation Excerpt :It is possible prior studies have not considered the role of sleep hygiene in encouraging regular physical activity. This potential role is compounded by the normative adverse effects of schizophrenia on sleep hygiene, as well as its related treatments, such as antipsychotics and early-morning medication administrations (Goldman et al., 1996; Reeve et al., 2015). Overall, we hypothesize through first improving sleep hygiene, including adequate sleeping durations, individuals diagnosed with schizophrenia would experience improved volition and be better prepared to engage in exercise regimens within experimental studies, resulting in the long-term maintenance of physical activity.
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2015, Psychiatric Clinics of North AmericaCitation Excerpt :The percentage of delta sleep at baseline predicted outcomes at 1 and 2 years.25 Studies found that the short REM-L was associated with poorer outcomes, including severe symptomatology, lack of employment, decreased social activity, and impaired global functioning.34,35 Evidence accumulated from PSG studies and their clinical correlates suggests that sleep structure abnormalities can serve as potential therapeutic targets or biomarkers in future investigations (Fig. 1).
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2013, Sleep Medicine ClinicsCitation Excerpt :Keshavan and colleagues104 reported that lower percentage of delta sleep at baseline predicted poorer functional outcomes at 1-year and 2-year follow-up. Another investigation found that shorter REM latency in medication-free inpatients with schizophrenia predicted poorer global functioning 1 year after hospital discharge.105 Similarly, relative to 6 inpatients with schizophrenia with sleep-onset REM episodes, 30 inpatients with schizophrenia without this sleep abnormality had better global functioning 1 year after assessment.106