ReviewAutoimmunity in heart disease: mechanisms and genetic susceptibility
References (43)
Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy
J. Am. Coll. Cardiol.
(1990)- et al.
Myocarditis and idiopathic dilated cardiomyopathy
Am. J. Med.
(1995) - et al.
Autoantibodies against human ventricular myosin in sera of patients with acute and chronic myocarditis
J. Am. Coll. Cardiol.
(1994) Induction of major histocompatibility complex antigens within the myocardium of patients with active myocarditis: a nonhistologic marker of myocarditis
J. Am. Coll. Cardiol.
(1990)- et al.
T cells in cardiac myosin-induced myocarditis
Clin. Immunol. Immunopathol.
(1993) The basis of autoimmunity: part I. Mechanisms of aberrant self-recognition
Immunol. Today
(1995)The basis of autoimmunity: part II. Genetic predisposition
Immunol. Today
(1995)- et al.
MHC genes in autoimmunity
Curr. Opin. Immunol.
(1993) Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene
Lancet
(1992)Detection of nephritogenic antigen from the Lewis rat renal tubular basement membrane
Kidney Int.
(1990)
Examination of characteristics that may distinguish disease-causing from benign AChR-reactive antibodies in experimental autoimmune myasthenia gravis
Adv. Neuroimmunol.
Myocarditis: a histopathologic definition and classification
Am. J. Cardiovasc. Pathol.
Autoimmune myocarditis: a murine model
Immunol. Ser.
The Ca2+-channel as cardiac autoantigen
Eur. Heart J.
Autoantibodies against the β-adrenergic receptor in human myocarditis and dilated cardiomyopathy: β-adrenergic agonism without desensitization
Eur. Heart J.
The significance of autoantibodies against the ADP/ATP carrier for the pathogenesis of myocarditis and dilated cardiomyopathy — clinical and experimental data
Springer Semin. Immunopathol.
Impaired myocyte function in vitro incubated with sera from patients with myocarditis
Eur. Heart J.
Phenotypic analysis of infiltrating cells in human myocarditis: an immunohistochemical study in paraffin-embedded tissue
Arch. Pathol. Lab. Med.
Myosin-induced acute myocarditis is a T-cell mediated disease
J. Immunol.
B-cell and T-cell function in systemic lupus erythematosus
Curr. Opin. Rheumatol.
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
J. Exp. Med.
Cited by (41)
Overview of pediatric myocarditis and pericarditis
2022, Progress in Pediatric CardiologyCitation Excerpt :In auto-immune disease and auto-immune reactions, there is damage due to antibodies exhibiting reactivity to cardiac antigens (for example Hashimoto thyroiditis and Grave's disease) and/or T cells targeting the myocardium [10,12]. These autoantibodies occur secondary to exposure to cardiac antigens, particularly in patients with a genetic predisposition to auto-immune disease [15]. In one recent study of 117 Lupus patients, the prevalence of myocarditis was assessed at 1.6% suggesting a significantly higher myocarditis risk for patients with auto-immune disease compared to the general population [16].
Molecular mapping of autoimmune B cell responses in experimental myocarditis
2007, Journal of AutoimmunityCitation Excerpt :The SEREX approach is not only well-suited for the identification of potential target antigens during autoimmune myocarditis, but permits as well a first fine mapping of the distinct seroepitopes. Our analysis indicates that the region between aa 600–1000, which encompasses the majority of the clones found (see Fig. 2), is most immunogenic and thereby corroborates the previously reported mapping of both B and Th cell epitopes in this region [11,19,44]. Taken together, the detailed molecular mapping of self-specific antibody responses during experimental myocarditis provides further evidence for the notion that virus infection-associated myocardial damage may trigger and perpetuate antibody formation against etiologically significant autoantigens.
Ca<sup>2+</sup> currents in cardiac myocytes: Old story, new insights
2006, Progress in Biophysics and Molecular BiologyCitation Excerpt :But an intriguing question remains: why do autoantibodies have deleterious effects on children while most mothers do not exhibit cardiac symptoms? A number of antibodies have been identified in sera from patients with myocarditis/dilated cardiomyopathy (for reviews see Malkiel et al., 1996; Caforio et al., 2002) and myocarditis/Chagas’ cardiomyopathy (reviewed by Kierszenbaum, 2003). Myocarditis is an inflammatory disease of the myocardium, and idiopathic, autoimmune, and infectious forms of inflammatory cardiomyopathy are recognized.
Gene expression in giant cell myocarditis: Altered expression of immune response genes
2005, International Journal of CardiologySpecialized CC-chemokine secretion by Th1 cells in destructive autoimmune myocarditis
2003, Journal of Autoimmunity