Original articleChildhood-onset uveitis in Behçet disease:a descriptive study of 36 cases☆
Section snippets
Methods
We performed a retrospective analysis of the medical records of 36 consecutive patients with childhood-onset ocular involvement of Behçet disease seen at the Uveitis Service, Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, between January 1975 and January 2002. Only patients who met the 1990 classification criteria of the International Study Group (ISG) for Behçet disease24 and who had uveitis at 16 years of age or younger were included in the study. Data
Results
The demographic features of the patients are shown in Table 1. Twenty-five patients were male, 11 were female. Mean age at presentation was 15.4 ± 3.3 years (range, 9–27). Mean age at onset of uveitis was 13.6 ± 2.1 years (range, 9–16). The initial symptom of Behçet disease was oral ulcers in 23 patients, genital ulcers in 2, both oral and genital ulcers in 3, skin lesions in 4, uveitis in 3, and arthritis in 1 patient. Twenty-one patients (58.3%) sought medical attention for the first time
Discussion
In the present study, only patients with childhood-onset Behçet uveitis selected through a uveitis service were analyzed, which may lead to a bias in drawing conclusions on the epidemiologic and systemic features of Behçet disease in this age group. Our male patients outnumbered female patients by a ratio of 2.3 to 1. Onset of uveitis was in late childhood. Bilateral panuveitis with retinal vasculitis and retinal infiltrates was the typical presentation. Although uveitis was the initial
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This study was supported by the Istanbul University Research Foundation (Project Number B-108/150499).