Elsevier

Fertility and Sterility

Volume 74, Issue 2, August 2000, Pages 282-287
Fertility and Sterility

In vitro fertilization
Blastocyst quality affects the success of blastocyst-stage embryo transfer

https://doi.org/10.1016/S0015-0282(00)00645-2Get rights and content
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Abstract

Objective:

To determine the relationship between blastocyst quality and the results of embryo transfer at the blastocyst stage.

Design:

Retrospective case analysis.

Setting:

Tertiary care private hospital IVF center.

Patient(s):

A total of 350 blastocyst-stage embryo transfer cycles.

Intervention(s):

In vitro culture to the blastocyst stage was undertaken in 350 ICSI cycles where four or more cleavage-stage embryos were available on day 3.

Main Outcome Measure(s):

Relationship between blastocyst quality and implantation and clinical and multiple pregnancy rates.

Result(s):

Transfer of at least one grade 1 or grade 2 blastocyst or one hatching blastocyst was associated with very high implantation and pregnancy rates. However, transfer of grade 3 blastocysts yielded very low implantation and pregnancy rates.

Conclusion(s):

There appears to be a strong correlation between blastocyst quality and success of blastocyst transfer.

Keywords

Blastocyst
intracytoplasmic sperm injection
implantation
pregnancy

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