Unstable trochanteric femoral fractures: extramedullary or intramedullary fixation: Review of literature
Introduction
Trochanteric fractures pose a challenge to the trauma surgeon in many ways: the nomenclature is often confusing, uniform classification is difficult because of the use of different classification systems, and the various treatment options are diverse, not evidence based and without consensus. An unstable trochanteric fracture adds to this, the challenge of a biomechanically very unfavourable fracture. A good treatment plan therefore starts with proper fracture classification.
Several trochanteric fracture classifications exist:21., 27., 33., 39., 40. the most basic and rational is to divide trochanteric fractures into stable or unstable fracture patterns.21., 27., 45., 55. In general, instability is determined by the presence of a zone of comminution of the medial cortex30., 34., 38., 39., 47., 50. and posterolateral instability.53 Nowadays, the most commonly used classification is that of the AO/ASIF group (Fig. 1).40 This classification has a good reproducibility48 as it basically divides the trochanteric fractures (type 31A) into three groups: A1 fractures (stable pertrochanteric fractures), A2 fractures (unstable pertrochanteric fractures with medial comminution including a fractured lesser trochanter) and A3 fractures (unstable intertrochanteric fractures with or without medial comminution). The instability of A2 and A3 fractures is created when one, or both, of the cortices is comminuted in a way that progressive (varus) displacement will follow unless intrinsic stability is provided by means of a stabilising implant. The forces that tend to displace the fracture must be neutralised by the implant. Theoretically, these forces are best transmitted through an implant close to the centre of axial loading, resulting in a shorter lever arm and a lower bending moment. The implant should, together with the fracture fragments, be able to bear full load. It should allow controlled fracture impaction (a gliding mechanism) in order to facilitate impaction and compression, therewith increasing stability. The risk of the implant cutting out in osteoporotic bone should be as small as possible and the periosteal blood supply should be disturbed as little as possible.57 Together, these demands stress the importance of an adequate interpretation of what may be expected (biomechanically) from a fracture–implant construct. The choice of implant depends on the degree of instability: the more unstable the fracture, the more stability is required of the method of fixation.
In general, for treatment of unstable trochanteric fractures two options exist: extramedullary or intramedullary stabilisation. The extramedullary option (Fig. 2) comprises any kind of sliding hip screw (SHS) connected to a plate at the lateral cortex: for instance the Dynamic Hip Screw® (DHS; Mathys Medical) or the Compression Hip Screw® (CHS; Smith and Nephew). The indicated advantages consist of the possibility of direct open fracture reduction and a relatively simple surgical technique, which is safe and very forgiving. The intramedullary method basically exists of a percutaneously inserted nail connected to one or more neck screws sliding through the nail. Examples of the intramedullary devices are the Gamma Nail® (Stryker Howmedica), the Intramedullary Hip Screw® (IMHS; Smith and Nephew) and the Proximal Femoral Nail® (PFN; Synthes), as shown in Fig. 3. The minimally invasive intramedullary technique is said to be associated with less blood loss and a lower infection rate, and the implant construction should allow direct full weight bearing because of its favourable biomechanical properties. Results of randomised clinical studies comparing the results of intramedullary and extramedullary fixation techniques for unstable trochanteric fractures are inconsistent and rare. Most comparative studies focus on treatment of stable trochanteric fracture types.3., 8., 31., 32., 41., 42., 44. We performed a literature review in an attempt to find consensus about the best treatment strategy for unstable trochanteric femoral fractures.
Section snippets
Methods
A Medline literature search was performed for prospective randomised clinical trials—comparing two basic methods of treatment for trochanteric femoral fractures—published since 1990. Studies comparing more than two treatment options in one randomised trial36., 37. were omitted, for reasons of statistical conflict using too small groups. There was no language restriction. The search term used was “trochanteric femoral fracture”, limited to randomised trials. We reviewed these articles for
Randomised clinical trials since 1990
The literature search revealed 20 prospective randomised clinical trials comparing two methods of treatment for unstable trochanteric femoral fractures, published since 1990. Two publications9., 10. reported only preliminary results or results of a trial that had been published before, and were therefore combined with the companion paper.11., 52.
Ten of the 18 remaining randomised trials did not analyse the results for unstable fractures separately from stable fractures. Results of these 10
IMHS versus sliding hip screw
Two randomised trials5., 29. compared the results of fracture fixation using the Intramedullary Hip Screw® with an (extramedullary) sliding hip screw. When stable and unstable fractures were examined separately, several differences became apparent in unstable fractures. The intramedullary device was associated with up to 23% less surgical time and up to 44% less blood loss compared to the SHS.5., 29. The IMHS was also associated with less impaction of the fracture and consequently, with less
Medial displacement osteotomy versus sliding hip screw
Focussing on extramedullary treatment options, Desjardins et al.17 reported on 109 unstable trochanteric fractures randomised for anatomical reduction (n=57) or valgus and medial displacement osteotomy (n=52), with sliding compression screw fixation in both groups. Although osteotomy is no longer used as standard treatment for unstable trochanteric fractures, it provides us with the basic insight in changing the biomechanical features in such a way that bending forces are converted into
Gamma Nail® versus Gliding Nail®
Fritz et al.24 performed a randomised clinical trial comparing two intramedullary devices: the Gliding Nail® and the Gamma Nail®, in 80 unstable trochanteric fractures. The Gliding Nail® consists of an intramedullary nail with a dynamic femoral neck blade. Operation time, blood loss (Table 2), weight bearing capacity and functional results were similar in both treatment groups. Mortality at 1 year (15%), hospital stay (10 days) and functional outcome were comparable for both treatment groups
Screw–plate systems
In a multicentre clinical trial Lunsjo et al.36 compared the efficacy of four extramedullary fixation systems, the Medoff sliding plate, the DHS, DHS with Trochanter Side Plate® (TSP; Synthes), and the DCS, in unstable trochanteric fractures. In 569 included patients, fixation failure rates varied from 4.6 to 8.2%, which is relatively low compared with the earlier published average fixation failure rates of the SHS systems in unstable fractures of about 10%.4., 8., 11., 17., 35., 56. The study
Discussion
This review was performed in an attempt to find evidence-based support for consensus of best treatment of unstable trochanteric femoral fractures and to discuss the current state of the art of treatment. There are some limitations to this review: literature since 1990 revealed a limited number of publications assessing too many different treatment methods to perform a systematic review. Moreover, methodology was found to be too defective for meta-analysis, as for instance, method of
Conclusions
The diversity of fixation devices available for treatment of unstable trochanteric femoral fractures illustrates the difficulties encountered in the actual treatment. Reduction in cut-out numbers will, however, hardly be accomplished by other and newer intramedullary implants, since optimal implants cannot make up for suboptimal fracture reduction or poor implant position. In view of the overall results of this literature review, routine use of intramedullary fixation devices is not to be
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