Elsevier

The Journal of Pediatrics

Volume 101, Issue 6, December 1982, Pages 948-952
The Journal of Pediatrics

Clinical and laboratory observation
Developmental deficits in iron-deficient infants: Effects of age and severity of iron lack

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    Prevention of anemia is important because anemia can lead to significant disability if untreated. Iron is necessary for early neurocognitive developmental processes during infancy and deficiency at this critical period can impair milestones and individual potential.2-9 Although iron deficiency may resolve spontaneously,17,19 the effect of undiagnosed and untreated iron deficiency during critical periods of infant growth and development place children at risk for permanent adverse cognitive effects.3,6

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Supported in part by grants from the Research Corporation, the Thrasher Research Fund, the Rockefeller Foundation, the Board of Trustees of Rainbow Babies and Childrens Hospital, and U.S. Public Health Services grants HD 14122, RR 07113, and LM 07001. Dr. Lozoff was an Andrew W. Mellon Scholar, Case Western Reserve University School of Medicine, 1980–1981; and Dr. Brittenham was a Teaching and Research Scholar in Medical Nutrition of the American College of Physicians, 1977–1980.

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