Clinical and laboratory observationDevelopmental deficits in iron-deficient infants: Effects of age and severity of iron lack†
References (14)
- et al.
The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infants
J Pediatr
(1982) - et al.
Significance of Bayley Scale score changes following iron therapy
J Pediatr
(1978) - et al.
Assessing iron status of a population
Am J Clin Nutr
(1979) - et al.
Effect of iron deficiency without anemia on infant behavior
Pediatr Res
(1981) - et al.
Iron deficiency and behavioral deficits
Pediatrics
(1981) - et al.
Behavioral abnormalities in infants with iron deficiency anemia
- et al.
Effect of the violation of assumptions upon significance levels of the Pearson r
Psychol Bull
(1977)
Cited by (68)
Fetal liver hepcidin secures iron stores in utero
2020, BloodCitation Excerpt :Suboptimal iron availability at birth is associated with cognitive, behavioral and motor skill deficits, and increased risk of developing anemia in infancy.1-7 Some of these developmental deficits are not reversible by oral iron therapy in the neonate.8-15 In the first 6 to 9 months of age, the neonate is not fully competent in regulating dietary iron absorption in response to iron needs16,17 and depends on liver iron stores to support its growth and development.18,19
Hematologic manifestations of systemic disease (including iron deficiency, anemia of inflammation and dic)
2013, Pediatric Clinics of North AmericaCitation Excerpt :The consequences of iron deficiency are systemic and include neurocognitive effects, epithelial changes, and the systemic consequences of anemia.13 Studies have repeatedly demonstrated that children with iron deficiency have an associated impaired motor and mental functioning.14–20 Effects on epithelial cells include angular stomatitis and glossitis.
Association between iron status and neurodevelopmental outcomes among VLBW infants
2010, Brain and DevelopmentAn Economic Analysis of Anemia Prevention during Infancy
2009, Journal of PediatricsCitation Excerpt :Prevention of anemia is important because anemia can lead to significant disability if untreated. Iron is necessary for early neurocognitive developmental processes during infancy and deficiency at this critical period can impair milestones and individual potential.2-9 Although iron deficiency may resolve spontaneously,17,19 the effect of undiagnosed and untreated iron deficiency during critical periods of infant growth and development place children at risk for permanent adverse cognitive effects.3,6
The economics of iron deficiency
2003, Food PolicyMicronutrient-fortified infant cereal improves Hb status and reduces iron-deficiency anaemia in Indian infants: An effectiveness study
2020, British Journal of Nutrition
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Supported in part by grants from the Research Corporation, the Thrasher Research Fund, the Rockefeller Foundation, the Board of Trustees of Rainbow Babies and Childrens Hospital, and U.S. Public Health Services grants HD 14122, RR 07113, and LM 07001. Dr. Lozoff was an Andrew W. Mellon Scholar, Case Western Reserve University School of Medicine, 1980–1981; and Dr. Brittenham was a Teaching and Research Scholar in Medical Nutrition of the American College of Physicians, 1977–1980.