Transendothelial transport (transcytosis) of iron—transferrin complex in the bone marrow1
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Gold nanoparticles: The importance of physiological principles to devise strategies for targeted drug delivery
2012, Nanomedicine: Nanotechnology, Biology, and MedicineCitation Excerpt :These studies suggested that these conjugates were internalized either by specific receptors (90%) in the vesicles that constitute transcytosis vesicles and also by fluid phase endocytosis (10%).10 Similar mechanisms of transcytosis were proposed for the transport of other molecules: low density lipoprotein (LDL), transferrin, and insulin.39-41 Au NPs interact with serum proteins and result in the adsorption of various serum proteins including albumin, and thus their fate in vivo is influenced by the serum proteins on the gold nano-surface.11
Low density lipoprotein binding induced asymmetric redistribution of the low density lipoprotein receptors in endothelial cells
1999, European Journal of Cell BiologyExploiting bone marrow microvascular structure for drug delivery and future therapies
1995, Advanced Drug Delivery ReviewsTransferrin Receptors in the Central Nervous System
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Supported by NIH Grant AM-30142 to M.T.
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