Low-density lipoprotein particle size and coronary artery disease in a childhood-onset type 1 diabetes population☆
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Cited by (26)
Type 1 Diabetes and Cardiovascular Health
2024, Endocrinology and Metabolism Clinics of North AmericaBody mass index and glycemic control influence lipoproteins in children with type 1 diabetes
2016, Journal of Clinical LipidologyCitation Excerpt :It is well known that in children with T1DM, the lipid levels are significantly influenced by glycemic control.9,10 Adults with T1DM are reported to have more atherogenic lipoprotein composition.11 Data from the SEARCH Case-Control Study revealed that youth with type 1 diabetes have significantly elevated apoB levels and more small, dense LDL particles than nondiabetic youth, regardless of glycemic control.7
Impact of low-density lipoprotein particle size on carotid intima-media thickness in patients with type 2 diabetes mellitus
2007, Metabolism: Clinical and ExperimentalCitation Excerpt :Small LDL particles are particularly prone to oxidation, providing a possible mechanism for their atherogenicity [2]. Therefore, LDL particle size has been increasingly recognized as a potential marker of increased risk for CVD [3-5]. On the other hand, oxidative modification of LDL [6-8] and glycated LDL [9] have been linked to the development of atherosclerosis and the increased incidence of CVD and myocardial infarction.
Effect of doxazosin on the size of LDL particle in the type 2 diabetic patients with hypertension
2000, Journal of Diabetes and its ComplicationsConcomitant reduction of low-density lipoprotein-cholesterol and biomarkers of inflammation with low-dose simvastatin therapy in patients with type 1 diabetes
2007, Journal of Clinical Endocrinology and Metabolism
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Supported by National Institutes of Health Grant No. DK-34818.