Ki-7 index as indicator of the post-surgical prognosis infeline mammary carcinomas
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Topoisomerase IIα immunoexpression in feline mammary carcinomas: A correlation with Ki67 immunoexpression and the mitotic count
2023, Research in Veterinary SciencePrognostic utility of preoperative neutrophil–lymphocyte ratio in cats with malignant mammary tumors
2021, Research in Veterinary ScienceCitation Excerpt :Several studies have investigated prognostic factors related to malignant FMTs, such as clinical staging, lymph node metastasis, intravascular invasion, tumor size, grading, multiple grand affected, and histochemical analyses, to determine their association with survival (Weijer and Hart, 1983; Ito et al., 1996; Castagnaro et al., 1998a; Castagnaro et al., 1998b; Castagnaro et al., 1998c; Millanta et al., 2002; Millanta et al., 2005; Millanta et al., 2006; Seixas et al., 2011). However, the studied prognostic factors were predominantly postoperative factors (Weijer and Hart, 1983; Ito et al., 1996; Castagnaro et al., 1998a; Castagnaro et al., 1998b; Castagnaro et al., 1998c; Millanta et al., 2002; Millanta et al., 2005; Millanta et al., 2006; Seixas et al., 2011), with only a few preoperative factors (Weijer and Hart, 1983; Ito et al., 1996; Seixas et al., 2011). Preoperative NLR can be measured inexpensively, easily, and quickly in veterinary clinical practice given that only leukocyte percentage is necessary for NLR measurements.
Mammary glands
2013, Feline Soft Tissue and General SurgeryPrognostic histopathological and molecular markers in feline mammary neoplasia
2012, Veterinary JournalCitation Excerpt :Ki67 staining in feline tissues is higher in mammary carcinomas than in benign lesions, and has also been correlated with histological grade of feline mammary carcinomas, with higher grade tumours exhibiting more cells with positive nuclear staining for MIB-1 (Dias Pereira et al., 2004; Morris et al., 2008). In a separate retrospective study, Ki67 staining was statistically different when the submissions were grouped according to survival at 1 year post-surgery (Castagnaro et al., 1998b). PCNA (synonym: polymerase delta associated protein) is an auxiliary subunit of DNA polymerase delta and is involved in DNA repair.
Oncology
2012, The CatOncology
2011, The Cat: Clinical Medicine and Management