CommentReassessing the hypothesis on STI control for HIV prevention
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Cited by (68)
Impact of a customized peer-facilitators training program related to sexual health intervention
2012, International HealthCitation Excerpt :Notably, HSV-2 seropositivity was found to have the highest risk.6 In spite of the strong evidence of the association between HIV and STI, there has been some debate majorly on causal relationship between HIV and STI7,8 and the importance of STI prevention as part of HIV programs; arguing that due to lack of evidence of impact, investment should be targeted towards interventions of proven efficacy.9 However, considering the strong evidence of the syndemic links between HIV and STI, and the heavy burden of disease posed by STI, it is paramount to include STI control in HIV programs, regardless of the causality between the two conditions as the mode of transmission and numerous risk factors are similar.
Living with uncertainty
2012, Trends in ParasitologyCitation Excerpt :Epidemics are complex, contingent systems; trials that attempt to change one part of that system may not be able to measure any effect of interventions because of confounding and delayed effects [40]. In addition to these epistemological problems, the ‘crucial experiment’ faces practical and ethical barriers that were also evident in STI treatment trials for HIV-prevention (Box 2) [45–47]. Because safe, efficacious, cost-effective treatments are available, it is unethical to withhold treatment.
Qualitative and quantitative intravaginal targeting: Key to anti-HIV-1 microbicide delivery from test tube to In Vivo success
2012, Journal of Pharmaceutical SciencesA review of female genital schistosomiasis
2012, Trends in ParasitologyCitation Excerpt :This may indicate that the lesion(s) around the eggs in genital mucosa provide an entry point for the HIV virus [26]. STD treatment studies have been marred by the lack of effect on the incidence of HIV infection [58]. These studies have generally been performed in schistosomiasis endemic areas.
The role of sexual networks in studies of how BV and STIs increase the risk of subsequent reinfection
2018, Epidemiology and InfectionFacing increased sexually transmitted infection incidence in HIV preexposure prophylaxis cohorts: What are the underlying determinants and what can be done?
2020, Current Opinion in Infectious Diseases