Elsevier

The Lancet

Volume 304, Issue 7884, 5 October 1974, Pages 826-829
The Lancet

Public Health
EVIDENCE FOR INAPPARENT RABIES INFECTION

https://doi.org/10.1016/S0140-6736(74)91084-8Get rights and content

Abstract

Evidence from laboratory and field studies of rabies in mouse, rat, guineapig, opossum, skunk, bat, bobcat, raccoon, fox, pig, dog, donkey, and man suggests that infection by rabies virus may lead to various outcomes—i.e., inapparent infection, survival with residual signs, or death. In the laboratory, inapparent infections were produced by aerosol inhalation and intramuscular injection of guineapigs, and by intraperitoneal inoculation of mice. Wild animals from rabies-endemic areas in the U.S.A. demonstrated evidence of previous contact with rabies virus, as did dogs in Ethiopia and Thailand and rodents in Thailand and Central Europe. Such evidence suggests exposure to rabies virus is more common in nature than previously believed. Knowledge about mechanisms underlying the different host responses may improve the chances of human survival after exposure to rabies virus.

References (41)

  • C. Yasmuth et al.

    Lancet

    (1970)
  • E.S. Tierkel

    Adv. vet. Sci.

    (1959)
  • I.H. Borts et al.

    Communicable and Infectious Diseases

  • P. Fenje

    Can. J, publ. Hlth

    (1968)
  • C. Yasmuth et al.

    J. med. Ass. Thailand

    (1974)
  • R.V. Blamire

    Postgrad. med. J.

    (1973)
  • M.M. Kaplan

    Nature

    (1969)
  • S.A. Plotkin et al.

    J. infect. Dis.

    (1971)
  • R.K. Sikes

    Am. J. publ. Hlth

    (1970)
  • J.F. Bell

    J. infect. Dis.

    (1964)
  • J.F. Bell et al.

    Am. J. Epidemiol.

    (1972)
  • J.B. Vaughn et al.

    J. Am. med. Ass.

    (1965)
  • R.K. Sikes

    Am. J. vet. Res.

    (1962)
  • D.H. Ferris et al.

    Cornell Vet.

    (1968)
  • V. Hronovsky et al.

    Acta Virol., Prague

    (1969)
  • W.G. Winkler et al.

    Am. J. Epidemiol.

    (1972)
  • O.A. Soave

    Am. J. vet. Res.

    (1964)
  • A.N. Nanavati

    Indian J. med. Sci.

    (1973)
  • C. Sérié et al.

    Annls Inst. Pasteur, Paris

    (1962)
  • A. Phuangsab et al.

    J. med. Ass. Thailand

    (1967)
  • Cited by (0)

    View full text