CORRELATION OF TYPE A BEHAVIOUR WITH ADRENERGIC RECEPTOR DENSITY: IMPLICATIONS FOR CORONARY ARTERY DISEASE PATHOGENESIS

doi:10.1016/S0140-6736(87)91421-8

The Lancet

Volume 330, Issue 8565, 24 October 1987, Pages 937-939

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Abstract

In 17 healthy young men who had a parent with documented early coronary disease, ratings of type A behaviour correlated with upregulated lymphocyte β₂ receptor density and inversely with the ratio of platelet α₂ to lymphocyte β₂ receptor density ratio. This indicates a correlation of type A behaviour with receptor-based determinations of increased peripheral α-adrenergic balance, consistent with increased coronary arterial vaso-constriction, perhaps leading to coronary artery disease.

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^☆: Preliminary data from this study were presented to the American Psychiatric Association, Chicago, May, 1987.

The Lancet

CORRELATION OF TYPE A BEHAVIOUR WITH ADRENERGIC RECEPTOR DENSITY: IMPLICATIONS FOR CORONARY ARTERY DISEASE PATHOGENESIS☆

Abstract