Original researchA multicenter, randomized, open-label, comparative, two-period crossover trial of preference, efficacy, and safety profiles of a prefilled, disposable pen and conventional vial/syringe for insulin injection in patients with type 1 or 2 diabetes mellitus☆
References (15)
- et al.
Insulin-pen treatment, quality of life and metabolic control: Retrospective intra-group evaluations
Diabetes Res Clin Pract
(1990) - et al.
Effect of patient-selected intensive insulin therapy on quality of life
Patient Educ Couns
(1997) - et al.
Comparison of NovoPen 3 and syringe/vials in the acceptance of insulin therapy in NIDDM patients with secondary failure to oral hypoglycaemic agents
Diabetes Res Clin Pract
(1998) - et al.
Do diabetic patients inject accurate doses of insulin?
Diabetes Care
(1981) - et al.
Accuracy of insulin injection in elderly patients
BMJ (Clin Res Ed)
(1983) - et al.
Experience of pain from insulin injections and needle-phobia in young patients with IDDM
Pract Diabetes Int
(1997) Coordinated approach to insulin transfer in the older type 2 client
J Diabetes Nurs
(1997)
Cited by (253)
A narrative literature review on traditional medicine options for treatment of corona virus disease 2019 (COVID-19)
2020, Complementary Therapies in Clinical PracticeBurden of insulin injection-related needlestick injuries in mainland China–prevalence, incidence, and healthcare costs
2019, International Journal of Nursing StudiesCitation Excerpt :Compared with the vial/syringe system, injection pens have multiple advantageous features, including but not limited to, ease of use, reduced the needle phobia, lower barriers in initiating insulin therapy, ease in transport and discreet use, and greater accuracy in insulin dosage (Asamoah, 2008). Numerous studies have confirmed that these benefits are associated with patient preference, treatment satisfaction, significant reduction in health care resource utilization, improved treatment adherence, reduced likelihood of experiencing a hypoglycemic event, and achieve better glycemic control (Korytkowski et al., 2003; Lee et al., 2006; Niskanen, 2010; Pawaskar et al., 2007). Findings from the recent worldwide insulin injection survey involving 13,289 diabetic patients (29% were Chinese patients) from 42 countries showed that 85.6% of patients used injection pen alone at the outpatient settings (Frid et al., 2016).
Development and Implementation of a Subcutaneous Insulin Pen Label Bar Code Scanning Protocol to Prevent Wrong-Patient Insulin Pen Errors
2019, Joint Commission Journal on Quality and Patient SafetyCentenary of Insulin Therapy: A Review
2024, Current Diabetes ReviewsDiabetes Technology: Standards of Care in Diabetes—2024
2024, Diabetes Care
- ☆
This study was presented as a poster at the European Association for the Study of Diabetes (EASD) Meeting, Budapest, Hungary, September 1–5, 2002.
- ∗
Members of the FlexPen® Study Team are listed in the Acknowledgments.