Research Paper
Complications following percutaneous liver biopsy: A multicentre retrospective study on 68 276 biopsies*

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Summary

This paper reviews the complications that arose after 68 276 percutaneous liver biopsies performed from 1973 to 1983. The complications are analyzed in relation to the underlying liver disease and to the type of needle used. Death was infrequent (9/100 000); it was always due to haemoperitoneum and occurred only in patients with malignant diseases or cirrhosis. Complications were less frequent in AVH (44/100 000) than in other liver diseases (from 125 to 278/100 000). Death, serious haemorrhagic complications, pneumothorax and biliary peritonitis were more frequent after biopsy with the Trucut needle than after biopsy with Menghini's needle (3/1000 against 1/1000).

Sixty-one percent of complications were discovered within two hours of biopsy and 96% within one day. The data indicate a post biopsy observation period of at least 24 hours. The day-case procedure should be reserved for patients not presenting liver tumour or cirrhosis.

References (30)

  • OzonoffM.B.

    Roentgenologic demonstration of intrahepatic hematoma following liver biopsy

    Amer. J. Dig. Dis.

    (1962)
  • ViranuvattiV. et al.

    Needle liver biopsy with particular reference to complications

    Amer. J. Gastroenterol.

    (1964)
  • PregerL.

    Hepatic arteriovenous fistula after percutaneous liver biopsy

    Amer. J. Roentgenol. Radium Ther. Nucl. Med.

    (1967)
  • CoxE.F.

    Hemobilia following percutaneous needle biopsy of the liver

    Arch. Surg.

    (1967)
  • JohnsonR.A. et al.

    Intrahepatic hematoma following liver biopsy by the Menghini technic

    Amer. J. Gastroenterol.

    (1968)
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    *

    This investigation was supported by C.N.R., Rome ‘Progetto Finalizzato Prevenzione delle Malattie da Infezione’, Grant No. 84.01865.52. The study was performed under the sponsorship of the Italian Association for the Study of the Liver (AISF).

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