Utility of the Serum Osmol Gap in the Diagnosis of Methanol or Ethylene Glycol Ingestion☆,☆☆,★
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Acknowledgements
The author gratefully acknowledges Richard Dart, MD, PhD, for his comments on the text and editing assistance.
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2022, Emergency Medicine Clinics of North AmericaCitation Excerpt :One problem with this equation is that the units are different, as the measured form is in units of osmolality (milliosmoles per kilogram) and the calculated form is in units of osmolarity (milliosmoles per liter). This unit difference is generally not considered significant for clinical purposes, and the gap may be expressed in either of the units; as a result, the osmol gap is interchangeably referred to as the osmolal or osmolar gap.41 Another important consideration is the timing of collection of samples.
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2021, Critical Care ClinicsCitation Excerpt :One problem with this equation is that the units are different, as the measured form is in units of osmolality (mOsm/kg) and the calculated form is in units of osmolarity (mOsm/L). This unit difference is generally not considered significant for clinical purposes, and the gap may be expressed in either of the units.39 Another important consideration is the timing of collection of samples.
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From the Denver Affiliated Residency in Emergency Medicine.
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Address for reprints: David S Glaser, MD, Kaiser Permanente Emergency Care Center, 1835 Franklin Street, Denver, Colorado 80218
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Reprint no. 47/1/70828