The epidemiology of dementia in Africa: a review
Introduction
The number of elderly people in Africa is increasing very rapidly. In Kenya and Zimbabwe, for example, the number of people aged 55 and over is expected to treble between 1988 and 2020. Official figures from the UN project life expectancy in Africa to increase from under 40 yr in 1950 to almost 60 in 2010. However, fertility rates continue to rise, so that over-65s will remain only a tiny proportion of the total population until well into the next millennium.
One of the major health problems associated with increasing numbers of elderly people is to create is a comparable increase in the number of sufferers from Alzheimer's Disease and other forms of dementia. Dementia is strongly related to old age, with numbers doubling with every 5 years of age (Jorm, 1990, Henderson, 1994) and at present there is no cure.
Over 100 studies of prevalence have been carried out; almost every part of the world has been surveyed (Ineichen, 1998b). Very few surveys have taken place in developing countries, despite the fact that by 2025, an estimated 68% of the world's elderly will be living in them (Chandra et al., 1994). Even in the developing country studied most thoroughly, China, nearly all the work has been done in cities (Ineichen, 1996).
Most surveys reveal relatively similar rates, given that fieldwork variables are seldom precisely comparable. Relatively few epidemiological studies of mental illness in Africa have centred on dementia, or indeed on more general psychogeriatric problems. However, most report low rates.
Section snippets
Evidence
One of the first major enquiries to mention mental health problems of the elderly was that of Yoruba people in Nigeria by Leighton et al. (1963). They report that there is no specific Yoruba word for senility, although the condition is easily recognised and described. It is well-known among Yoruba that older people become childish, do not answer questions properly, ‘beat about the bush’ in their talk, cannot remember things, and in general lose their mental capacities. This is regarded as a
Discussion
Nigeria is the only African country which has reported a substantial amount of research on the subject of the prevalence of dementia. Some of the research evidence is puzzling. Cultural attitudes in Nigeria surrounding dementia may be an influence, and as these may be widespread throughout Africa, their significance could extend beyond Nigeria. If rates are genuinely low, this could be a pointer towards causality. These findings are worth examining. What precisely is going on?
Only a few studies
Conclusion
African research has indicated an unclear picture with respect to dementia. Rates appear to be low, and very low indeed for Alzheimer's Disease. If this finding is genuine, it may prove to be a significant lead in the search for the cause of Alzheimer's Disease, or for environmental or genetic influences on its progress.
The association of APOE genotype E4 and dementia found in studies of white populations received confirmation among African-Americans (Hendrie et al., 1995b) but not among
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