Research section13-Week inhalation toxicity study of menthol cigarette smoke☆
References (26)
- et al.
Menthol and nonmenthol cigarettes and smoke exposure in black and white women
Pharmacology, Biochemistry and Behavior
(1996) - et al.
Histologic changes in the respiratory tract induced by inhalation of xenobiotics: physiologic adaptation or toxicity?
Toxicology and Applied Pharmacology
(1989) - et al.
Chronic inhalation study in rats using cigarettes containing different amounts of Cytrel tobacco supplement
Toxicology
(1982) - et al.
Regional differences in the effects of mainstream cigarette smoke on stored mucosubstances and DNA synthesis in F344 rat nasal respiratory epithelium
Toxicology and Applied Pharmacology
(1995) - et al.
Mentholated cigarettes decrease puff volume of smoke and increase carbon monoxide absorption
Physiology and Behavior
(1994) Monographs on fragrance raw materials: /-Menthol
Food and Cosmetics Toxicology
(1976)Monographs on fragrance raw materials: Menthol racemic
Food and Cosmetics Toxicology
(1976)Acute carbon monoxide poisoning in an animal model: the effects of altered glucose on morbidity and mortality
Toxicology
(1993)- et al.
Inhalation bioassay of cigarette smoke in rats
Toxicology and Applied Pharmacology
(1981) Histopathologic examination of the rat nasal cavity
Fundamental and Applied Toxicology
(1981)
Nose-only exposure of rats to carbon monoxide
Inhalation Toxicology
Description of a continuous-smoking inhalation machine for exposing small animals to tobacco smoke
Beiträge zur Tabakforschung
A bronchomucotropic action in rabbits from inhaled menthol and thymol
Archives Internationales de Pharmacodynamie et de Thérapie
Cited by (63)
Investigation of menthol content and transfer rates in cigarettes and Tobacco Heating System 2.2
2019, Regulatory Toxicology and PharmacologyA 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology
2018, Food and Chemical ToxicologyA 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment
2018, Food and Chemical ToxicologyCitation Excerpt :These measurements were further complemented by lipidomic profiling of lung tissues. Histopathological evaluation of the RNE showed commonly observed adaptive changes after CS exposure (Kogel et al., 2014; Gaworski et al., 1997; Vanscheeuwijck et al., 2002), with squamous cell metaplasia and basal cell hyperplasia as the most pronounced exposure effects. At a matching nicotine concentration between CHTP1.2 aerosol and CS (23 μg nicotine/L), CHTP1.2 aerosol induced less pronounced histological changes, with only the basal cell hyperplasia severity scores for the highest CHTP1.2 concentration (50 μg nicotine/L) approaching those of 3R4F (23 μg nicotine/L) in nose level 1.
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Presented at the International Congress of Toxicology, 7th Meeting, 1–6 July 1995, Seattle, Washington, USA.