5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa
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Cited by (101)
Association of 5-HTR2A -1438A/G polymorphism with anorexia nervosa and bulimia nervosa: A meta-analysis
2021, Neuroscience LettersAnxiolytic-like effects of leptin on fixed interval responding
2016, Pharmacology Biochemistry and BehaviorConceptualizing the role of estrogens and serotonin in the development and maintenance of bulimia nervosa
2010, Clinical Psychology ReviewGenetic Findings in Anorexia and Bulimia Nervosa
2010, Progress in Molecular Biology and Translational ScienceCitation Excerpt :Association with AN was shown for the A-allele of the promoter polymorphism (− 1438G>A) of the 5-HT2A receptor gene (HTR2A).65 Whereas some of the replication studies confirmed this result,66–69 others did not.70–74 Additionally, an early meta-analysis showed a lack of association.75
The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating
2009, Journal of Psychiatric ResearchCitation Excerpt :Most studies of the 5-HT2a receptor gene have examined a single nucleotide polymorphism (SNP) in the promoter region (−1438G/A). Six studies report no association with BN and/or binge eating (Bruce et al., 2005; Enoch et al., 1998; Fuentes et al., 2000; Nacmias et al., 1999; Ricca et al., 2002; Ziegler et al., 1999), while two studies found a higher frequency of the A allele in individuals with BN compared to controls (Ricca et al., 2002, 2004). By contrast, a significant association between BN and the G allele of the −1438G/A SNP has also been reported (Nishiguchi et al., 2001).
The serotonin 2A receptor gene in alcohol dependence and tobacco smoking
2009, Drug and Alcohol Dependence