Clinical studies
Treatment and blood pressure control in 47,964 people with diabetes and hypertension: A systematic review of observational studiesTraitement et maîtrise de lhypertension chez 47 964 diabétiques hypertendus : Revue systématique des études dobservation

https://doi.org/10.1016/S0828-282X(06)70304-XGet rights and content

Background

Many patients with diabetes also have hypertension, greatly increasing their risk for cardiovascular disease. It has been suggested that hypertension is poorly treated in those with diabetes.

Objective

To examine treatment and control of hypertension in people with diabetes.

Data Sources

Data sources included MEDLINE, EMBASE, HealthSTAR, CINAHL, Web of Science, clinical evidence and government health and statistical Web sites.

Method

Databases were systematically reviewed and hand searches of the bibliographies of relevant studies (1990 to 2004) were conducted. Two investigators selected studies and extracted the data independently.

Results

A total of 44 studies (77,649 subjects with diabetes, 47,964 [62%] of whom also had hypertension) were included. While 83% (range 32% to 100%) of patients with hypertension received drug therapy, only 12% (range 6% to 30%) had their blood pressure (BP) controlled to 130/85 mmHg or less. While BP control rates differed by definition of control (those studies with the least stringent definitions for BP control – 160/90 mmHg or less – reported mean control rates of 37%), treatment and control rates did not differ appreciably between countries or health care settings.

Conclusions

Fewer than one in eight people with diabetes and hypertension have adequately controlled BP, with remarkable uniformity across studies conducted in a variety of settings. There is an urgent need for multidisciplinary, community-based approaches to manage these high-risk patients.

Historique

De nombreux diabétiques hypertendus se trouvent exposés à un risque beaucoup plus grand de maladie cardiovasculaire et selon certains, lhypertension serait mal maîtrisée chez les sujets diabétiques.

Objectif

Analyser le traitement et la maîtrise de lhypertension chez les diabétiques.

Sources Des Données

Parmi les sources des données, mentionnons MEDLINE, EMBASE, HealthSTAR, CINAHL, Web of Science, les résultats détudes cliniques et les statistiques de santé présentées dans divers sites Web gouvernementaux.

Méthode

Les auteurs ont interrogé les bases de données de manière systématique et ont procédé à des recherches manuelles à partir des bibliographies des études pertinentes (1990 à 2004). Deux chercheurs se sont chargés de sélectionner les études et den extraire les données de manière indépendante.

Résultats

En tout, 44 études (77 649 sujets diabétiques, dont 47 964 [62 %] souffraient aussi dhypertension) ont été incluses. Bien que 83 % (entre 32 % et 100 %) des patients hypertendus aient été sous traitement médicamenteux, 12 % seulement (entre 6 % et 30 %) présentaient une tension artérielle (TA) maîtrisée, soit 130/85 mm Hg ou moins. Malgré le fait que le degré de « contrôle de la TA » ait différé selon la définition donnée dans chaque étude (celles dont la définition du contrôle de la TA était la moins stricte, soit 160/90 mm Hg ou moins, ont signalé des taux de contrôle moyen de 37 %), les taux de traitement et de maîtrise nont pas différé de manière notable entre les pays ou les types détablissements de soins de santé.

Conclusion

Moins dune personne sur huit souffrant à la fois de diabète et dhypertension présentait une TA adéquatement maîtrisée et ce, avec une homogénéité remarquable entre les études réalisées dans des milieux divers. Il faut donc de toute urgence mettre en oeuvre des approches pluridisciplinaires dans les collectivités si lon veut arriver à prendre efficacement en charge ces patients à haut risque.

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