2000 Special IssueTowards a network theory of cognition
Section snippets
Connectivity maximizes flexibility of information processing and representation
One prominent feature of the brain is connectivity. Neurons are linked to one another both locally and at a distance. Most other systems in the body show some capacity for cell to cell communication, but the nervous system appears to be specialized for rapid transfer of signals. Physiologically, this means that a single change to the system is conveyed to several parts of the brain simultaneously and that some of this will feed back onto the initial site. There are obvious extremes to just how
Transient response plasticity in the CNS is ubiquitous
Neural plasticity is an established phenomenon. Following central or peripheral damage there is profound reorganization of the nervous system (Hubel and Wiesel, 1965, Merzenich et al., 1983, Pons et al., 1991. Reorganization also can be observed after prolonged training (Karni et al., 1995). The plasticity considered here is more short-lived. Cells can show a rapid shift in response to afferent stimulation that is dependent on the context in which they fire. This transient response plasticity
Aggregate properties of neural populations
The idea of “neural aggregates” has some history and has been used to characterize brain theories that strike an intermediate position between strict localization of function and a holistic approach. Aggregate theories acknowledge that certain functions, usually sensory and motor, may be localizable, but higher-order function results from the combined, or aggregate, operations of several areas (Lashley, 1929). Recent examples of aggregate theories state that cognitive processes result from the
Neural context
The idea of a neural context is meant to underscore the importance of considering activity of the entire brain rather than individual regions. Activity of the area may be equivalent across several seemingly different cognitive tasks. What distinguishes tasks is the pattern of spatiotemporal activity and interactivity more than the participation of any particular region. Through its connectivity and basic response properties, large neural systems are engaged starting from the sensory systems,
Implications for cognition
Neurophysiology and cognitive psychology have developed independently across the centuries. There is no necessity for the two disciplines to influence each other. Neurophysiology has evolved partly from study of the basic properties of neurons without much link to overt behaviour beyond simple reflexes. Conversely, cognitive psychology has developed through careful experimental investigation of overt behaviour and how the manipulations of putative cognitive processes change the measured
Acknowledgements
The contributions of several of my colleagues to the development of the ideas expressed here are gratefully acknowledged: Drs B. Horwitz, JM Jennings, E Tulving, L Nyberg, R Cabeza, and NJ Lobaugh. AR McIntosh is supported by the Natural Sciences and Engineering Council of Canada and the Medical Research Council of Canada (grant MT-13623).
References (86)
- et al.
Classical conditioning induces CS-specific receptive field plasticity in the auditory cortex of the guinea pig
Brain Research
(1990) - et al.
Response suppression, initiation and strategy use following frontal lobe lesions
Neuropsychologia
(1996) - et al.
Human prefrontal cortex is not specific for working memory: a functional MRI study
Neuroimage
(1998) - et al.
Competitive brain activity in visual attention
Current Opinion in Neurobiology
(1997) - et al.
The trouble with cognitive subtraction
Neuroimage
(1996) Transients, metastability, and neuronal dynamics
Neuroimage
(1997)Associative and perceptual learning and the concept of memory systems
Cognitive Brain Research
(1996)- et al.
Identification of functionally related neural assemblies
Brain Research
(1978) - et al.
Mapping neural interactivity onto regional activity: an analysis of semantic processing and response mode interactions
Neuroimage
(1998) - et al.
Cognitive subtractions may not add up: the interaction between semantic processing and response mode
NeuroImage
(1997)
Consciousness and cognition may be mediated by multiple independent coherent ensembles
Conscious Cognition
Progression of change following median nerve section in the cortical representation of the hand in areas 3b and 1 in adult owl and squirrel monkeys
Neuroscience
Deficits in associative-learning tasks after frontal- and temporal-lobe lesions in man
Neuropsychologia
A critical review of PET studies of phonological processing
Brain and Language
Population coding by cell assemblies — what it really is in the brain
Neuroscience Research
Physiological plasticity in auditory cortex: rapid induction by learning
Progress in Neurobiology
Hippocampus and medial temporal cortex: neuronal activity related to behavioural responses during the performance of memory tasks by primates
Behavioral Brain Research
The complex structure of a simple memory
Trends in Neuroscience
Dynamics of neuronal firing correlation: modulation of effective connectivity
Journal of Neurophysiology
How does a serial, integrated and very limited stream of consciousness emerge from a nervous system that is mostly unconscious, distributed, parallel and of enormous capacity?
Ciba Foundation Symposium
Brain regions responsive to novelty in the absence of awareness
Science
Plasticity and localization theory
Modulation of connectivity in visual pathways by attention: Cortical interactions evaluated with structural equation modeling and fMRI
Cerebral Cortex
Functional neuroanatomy of recall and recognition: a PET study of episodic memory
Journal of Cognitive Neuroscience
Imaging cognition: an empirical review of PET studies with normal subjects
Journal of Cognitive Neuroscience
Is cognitive neuropsychology plausible?
Journal of Cognitive Neuroscience
Stochastic resonance without tuning
Nature
Selective and divided attention during visual discriminations of shape, color, and speed: functional anatomy by positron emission tomography
Journal of Neuroscience
Visual properties of neurons in area V4 of the macaque: Sensitivity to stimulus form
Journal of Neurophysiology
Motor areas of cerebral cortex
Journal of Clinical Neurophysiology
Noise enhancement of information transfer in crayfish mechanoreceptors by stochastic resonance
Nature
Rapid development of learning-induced receptive field plasticity in the auditory cortex
Behavioral Neuroscience
Group selection and phasic re-entrant signalling: a theory of higher brain function
Distributed hierarchical processing in the primate cerebral cortex
Cerebral Cortex
Brain systems for encoding and retrieval of auditory-verbal memory: an in vivo study in humans
Brain
Functional and effective connectivity: A synthesis
Human Brain Mapping
Imaging cognitive anatomy
Trends in Cognitive Sciences
Time-dependent changes in effective connectivity measured with PET
Human Brain Mapping
Memory and planning: two temporal perspectives of frontal lobe function
Neuronal population coding of movement direction
Science
Cognitive neurophysiology of the motor cortex
Science
Cellular and circuit basis of working memory in prefrontal cortex of nonhuman primates
Neural systems for encoding and retrieving new long-term memories: a PET-rCBF study
Investigations in Ophthalmic Vision Science
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