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2016, Nutrition ResearchCitation Excerpt :The recommendation for Vitamin E intake was 15 mg/day for adults 19 to 50 years of age [44] but data from the NHANES 2003–2006 indicated that Americans consumed about 7 mg/day [45]. Nonetheless, signs of overt Vitamin E deficiency were rare and usually associated with malnutrition, rare genetic conditions, and certain chronic diseases [46-50]. While observational epidemiological studies suggested that Vitamin E may reduce cardiovascular events, large randomized prospective cohort trials have generally not demonstrated favorable effects on cardiovascular disease [51-53].
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