LetterEvaluation of a synergistic combination between the non-antibiotic microbicides diclofenac and trifluoperazine
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2021, International Journal of Antimicrobial AgentsActivity of diclofenac used alone and in combination with streptomycin against Mycobacterium tuberculosis in mice
2007, International Journal of Antimicrobial AgentsCitation Excerpt :The anti-inflammatory drug diclofenac sodium (DCL) possesses powerful biocidal activity towards Gram-positive and Gram-negative bacteria [2,3] and mycobacteria [4]. It was synergistic with streptomycin (STM) against Mycobacterium smegmatis [5] and strains of Escherichia coli and Staphylococcus aureus, and also with a non-antibiotic trifluoperazine against some Gram-positive and Gram-negative bacteria [6,7]. Prolonged and widespread use of STM as monotherapy in tuberculosis has resulted in an average of 1 in 108 tubercle bacilli being resistant to STM at 10–100 μg/mL.
Antibacterial property of the antipsychotic agent prochlorperazine, and its synergism with methdilazine
2005, Microbiological ResearchAn Exploratory Study on the Antimicrobial Activity of Cetirizine Dihydrochloride
2017, Indian Journal of Pharmaceutical SciencesAlterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac
2011, Annals of Clinical Microbiology and Antimicrobials
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