Eosinophils in allergic reactions

https://doi.org/10.1016/S0952-7915(96)80006-9Get rights and content

Abstract

Mainly located in the skin or mucosa of patients with allergic diseases, eosinophils contribute directly to tissue damage and chronic inflammation. The past year has seen significant advances in the study of the factors involved in the specific tissue recruitment of eosinophils, including chemoattractants and their receptors. New data have been obtained on the synthesis by eosinophils of various cytokines mostly released by immune complexes.

References (59)

  • E Delaporte et al.

    IgE autoantibodies directed against the major bullous pemphigoid antigen in patients with a severe form of pemphigoid

    J Immunol

    (1996)
  • B Wallaert et al.

    Immunoreactivity for interleukin-3, -5 and granulocyte-macrophage colony stimulating factor of intestinal mucosa in bronchial asthma

    J Exp Med

    (1995)
  • P Desreumaux et al.

    Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease

    J Exp Med

    (1992)
  • S Sullivan et al.

    Compartmentalization of eosinophil granulocyte-macrophage colony-stimulating factor expression in patients with asthma

    J Allergy Clin Immunol

    (1996)
  • H Nakajima et al.

    Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment in the tissue

    J Exp Med

    (1994)
  • BS Bochner et al.

    IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells

    J Immunol

    (1995)
  • MB Resnick et al.

    Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor

    Gastroenterology

    (1995)
  • DH Broide et al.

    Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics

    J Clin Invest

    (1992)
  • GM Walsh et al.

    IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner

    Immunology

    (1990)
  • CL Elbon et al.

    Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs

    Am J Resp Cell Mol Biol

    (1995)
  • Y Tanaka et al.

    Interleukin-5 messenger RNA and immunoreactive protein expression by activated eosinophils in lesional atopic dermatitis skin

    J Invest Dermatol

    (1994)
  • S Dubucquoi et al.

    Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease

    Gut

    (1995)
  • M Weber et al.

    Basophil and eosinophil activation by CC chemokines

    Int Arch Allergy Immunol

    (1995)
  • N Noso et al.

    Human monocyte chemotactic proteins-2 and 3 (MCP-2 and MCP-3) attract human eosinophils and desensitize the chemotactic responses towards RANTES

    Biochem Biophys Res Commun

    (1994)
  • S Ying et al.

    The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosinophil, T cell, and macrophage recruitment

    J Exp Med

    (1995)
  • NW Lukacs et al.

    Macrophage inflammatory protein-1 α influences eosinophil recruitment in antigen-specific airway inflammation

    Eur J Immunol

    (1995)
  • R Alam et al.

    Increased MCP-1, RANTES, and MIP-1α in bronchoalveolar lavage fluid of allergic asthmatic patients

    Am J Respir Crit Care Med

    (1996)
  • ME Rothenberg et al.

    Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung

    J Exp Med

    (1995)
  • EA Garcia-Zepeda et al.

    Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

    Nat Med

    (1996)

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