Transcriptional Regulation: Flipping the Myc switch

doi:10.1016/S0960-9822(95)00173-4

Current Biology

Volume 5, Issue 8, August 1995, Pages 859-861

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Abstract

When certain cells differentiate, Myc in Myc–Max heterodimers is replaced by Mad or Mxi, generating heterodimers that suppress transcription by interacting with the repressor Sin3.

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René Bernards, Division of Molecular Carcinogenesis, Netherlands Cancer Institute, 121 Plesmanlaan, 1066 CX Amsterdam, The Netherlands.

Current Biology

DispatchTranscriptional Regulation: Flipping the Myc switch

Abstract

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Transcriptional Regulation: Flipping the Myc switch