Current Biology
Volume 9, Issue 15, 12 August 1999, Pages R568-R571
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Receptor signaling: When dimerization is not enough

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Abstract

Activation of receptors that signal via tyrosine kinase domains has been thought to involve receptor dimerization and transphosphorylation of juxtaposed catalytic domains. Recent results suggest things might be more complex – specific intersubunit conformational changes within a dimer can also be important.

Keywords

Biochemistry
Cell Biology

Cited by (0)

G Jiang and T Hunter, Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

E-mail address for T Hunter (corresponding author): [email protected].