Trends in Biochemical Sciences
Research UpdateJmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2β
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Acknowledgments
The authors are funded by the UK Medical Research Council. We would like to acknowledge the helpful comments of an anonymous reviewer.
References (18)
- et al.
Evidence of domain swapping within the jumonji family of transcription factors
Trends Biochem. Sci.
(2000) Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2
J. Biol. Chem.
(1999)Molecular characterization of cytosolic phospholipase A2-β
J. Biol. Chem.
(1999)The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation
Am. J. Pathol.
(1999)- et al.
Prediction of protein secondary structure at better than 70% accuracy
J. Mol. Biol.
(1993) ARID proteins come in from the desert
Trends Biochem. Sci.
(2000)Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Nucleic Acids Res.
(1997)Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks
Proc. Natl. Acad. Sci. USA
(1994)Microbial relatives of the seed storage proteins of higher plants: Conservation of structure and diversification of function during evolution of the cupin superfamily
Microbiol. Mol. Biol. Rev.
(2000)
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2019, GeneCitation Excerpt :Finally, the fact that no conserved domains are detected on kdm9 might be due to the incomplete gene sequence/annotation. Presence of the JmjC domain on all other rivulus putative Kdm members suggests that they are active proteins (Clissold and Ponting, 2001), and additional evolutionarily conserved domains (Jmj, Arid) confirm homology with their orthologues (Klose et al., 2006; Takeuchi et al., 2006). While, teleost species have undergone a 3R genome duplication event, and even a 4R-duplicated genome for salmoniforms (Best et al., 2018), it was important to investigate the gene evolution of the rivulus Kdm proteins.