Elsevier

Microbes and Infection

Volume 2, Issue 5, April 2000, Pages 533-542
Microbes and Infection

Review
Bacterial ureases in infectious diseases

https://doi.org/10.1016/S1286-4579(00)00312-9Get rights and content
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Abstract

Ureases are multi-subunit, nickel-containing enzymes that catalyze the hydrolysis of urea to carbon dioxide and ammonia. This brief review discusses the biochemistry and genetics of bacterial ureases and outlines the roles of urea metabolism in microbial ecology and pathogenesis of some of the principle ureolytic species affecting human health.

Keywords

Helicobacter
oral microbes
ecology
pathogenesis
urinary tract

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